Esomeprazole Magnesium Pellets

Esomeprazole Magnesium PelletsEsomeprazole is a proton pump inhibitor which is used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome.

Esomeprazole is the S-enantiomer of omeprazole and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic mixture of omeprazole. However, this greater efficacy has been disputed, with some claiming it offers no benefit from its older form.

Esomeprazole is a proton pump inhibitor which reduces acid secretion through inhibition of ATPase in gastric parietal cells. By inhibiting the functioning of this enzyme, the drug prevents formation of gastric acid.

Dose:
Esomeprazole Magnesium 40 mg

Available Form:
Esomeprazole Magnesium Pellets
We also offer Sustained (SR) / Immediate (IR) / Timed (TR) / Controlled (CR) / Delayed Release (DR) and Enteric Coated (EC).

Umang Pharmatech equipments used for production of Esomeprazole Magnesium Pellets:
DRUG LAYERING : Esomeprazole Magnesium pellets can be made by Drug layering method by a suitable drug layering equipment Made by UMANG PHARMATECH, The powder is sprinkled from one side in a drug layering machine and liquid from the other side.

FLUID BED DRYER : Esomeprazole Magnesium pellets can be dried in a fluid bed dryer.

SEIVING AND BLENDING : All pellets are seived to a particular size and blended into a batch to suit the customer size and capsule fill weight required.

FLUID BED PROCESSOR : For bottom spray coating to be done on pellets, depending on the process and requirement of the product.

To view the complete list of equipments please visit our site : WWW.UMANGPHARMATECH.COM

Solutions from us :
  • Making ready to fill pellets / compressible granules.
  • Making process suitability for your products.
  • Deciding the right kind of technology / equipments for the products.
  • Process Validation & Stability.
  • Documentation.
  • Technology transfer of products with complete line of equipments.
  • Doessair preparation.
  • Validation and regulatory support.


  • Esomeprazole Magnesium
    Systematic (IUPAC) Name
    Esomeprazole Magnesium
    Identifiers
    Esomeprazole Magnesium
    Chemical data
    (S)-5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
    CAS number : 119141-88-7
    ATC code : A02BC05
    PubChem : CID 9579578
    DrugBank : APRD00363
    ChemSpider : 7853936
    UNII : N3PA6559FT
    KEGG : D07917
    ChEMBL : CHEMBL1201320
    Formula : C17H19N3O3S
    Mol. mass : 345.417 g/mol
    * All transactions are carried out in conformity with patent laws applicable in the user country. Active pharmaceutical ingredients or formulations thereof will not be supplied in countries where the same is under patent protection except as and if permitted under law of the country for research and development purposes only.
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