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Calcium Carbonate Spheres

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Calcium Carbonate Spheres

Segment : Neutral Spheres


Size : 75-212 μm, 106-212 μm, 150-300 μm, 500-710 μm, 710-850 μm

Available Strength : 100%

Product Code : 01{confidential}

Featured Information On calcium carbonate Spheres

Successful formulation of novel actives necessitates safe application and high excipient levels. Spheres are adaptable beginning cores for a variety of unique dose forms.

Calcium carbonate spheres are an inert base for modified release formulations derived from natural sources, including marble, limestone, and other forms in the Earth's crust. They support uniform drug release profiles, resulting in a consistent therapeutic response. In tablet preparations, these spheres also serve as antacids, laxatives, binding substances, and fillers.

Calcium carbonate spheres are also recognized for their tasteless, odourless, safe, low-cost, and eco-friendly nature. It enhances the solubility of pH-sensitive active pharmaceutical ingredients (APIs) by creating an alkali micro-environment around the sphere. This micro-environment increases the solubility of active pharmaceutical ingredients (APIs) that specifically require an alkaline environment for optimal dissolution. The calcium carbonate spheres are biodegradable in nature and are easily metabolized and eliminated from the body. Thus minimizing the risk of long-term accumulation in the body.

At Umang Global, we specialize in offering Calcium carbonate spheres with customized solutions and reproducible particle size distribution. Our manufacturing site is dedicated to the pharmaceutical production of calcium carbonate spheres. So you can be confident that it meets the lowest microbial loads.

Micro pellets (100 μm - 200 μm) for highly active low dosage API. Perfect tool for combinatory and controlled release products. Wide range of particle size fractions with uniform spherical shape and structure. Narrow particle size distribution within each fraction. Spheres ® are made under GMP conditions with Calcium Carbonate from certified suppliers.

Quality analyzed according to Ph. EU., USP/NF. Formulation of sensitive actives due to the inertness of Calcium Carbonate. High abrasion resistance improves and simplifies the coating process.

Ideal for capsules. Spheres ® show excellent compact ability due to the high plasticity of Calcium Carbonate Spheres ®. Higher payload permits smaller capsule sizes.

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Benefits of calcium carbonate sphere

  • Chemically and biologically inert.
  • Biodegradable and easily metabolized in the body.
  • Wide range of particle size fractions with perfect spherical shape and structure
  • Low friability and high mechanical strength
  • Calcium carbonate spheres are odourless and tasteless.
  • Allergen-free, Gluten-free, Sugar-free
  • Enhances the solubility of pH-sensitive drugs.

Reasons to use calcium carbonate sphere.

  • Customized Release Profile
  • Total Compliance with EP, USP, IP
  • Outstanding microbiological quality
  • Higher Drug Stability
  • Safe, Low-cost, and Eco- friendly nature
  • Worldwide acceptance

Regulatory Information of calcium carbonate sphere

  • CNS- No. 471-34-1
  • In compliance with EP, USP, IP.
  • BSE/TSE free
  • Allergen free, Gluten free, Sugar free
  • Residual Solvent free

Storage conditions for calcium carbonate sphere:

  • Protect from excessive temperature
  • Protect from moisture
  • Protect from freezing
  • Re-evaluation 36 months from date of manufacturing

General properties related to Neutral Spheres


  • Narrow particle size distribution
  • Even and dense surface
  • Perfect sphericity
  • Low friability
  • Inertness


  • Pharmaceutical Industry
  • Cosmetics Industry
  • Food Industry

Formats Available

  • Micro Encapsulate
  • Beadlets
  • Spheres
  • Enteric Coated
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