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Microcrystalline cellulose (MCC) Spheres

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Microcrystalline cellulose (MCC) Spheres

Segment : Neutral Spheres


Size : 100-200 μm, 200-355 μm, 350-500 μm, 500-710 μm, 700-1000 μm, 1000-1400 μm

Available Strength : 100%

Product Code : 01{confidential}

Featured Information On Microcrystalline cellulose (MCC) Spheres

Multi-particulate systems are comprised of small, discrete drug particles. They are gaining popularity due to their versatility, flexibility, and precise dosing; compared to monolithic dosage forms, they offer improved drug release control and a more consistent therapeutic effect, allowing for reduced dosing frequency and potentially minimizing side effects.

Neutral cores - As an inert odourless and tasteless excipient MCC is extremely versatile.

MCC spheres are free-flowing spherical masses of pure Microcrystalline cellulose (USP, IP). They are uniform in size, making them extremely robust, chemically inert, and suitable for various active ingredients. Our Encapsulated MCC Spheres can help you achieve your ideal multi-particulate formulation without hassle. With low chemical reactivity, these MCC pellets are a safe and easy way to create multi-particular dosage forms.

At umang global we specializes to offer MCC spheres with a customized solutions and reproducible particle size distribution. Our spheres are made from certified MCC and pure water allowing you to multiply the benefits of neutral pellets with the unbeatable properties of MCC. Altogether, this means higher safety, better compliance, and added value for your products.

Microcrystalline cellulose (MCC) spheres are tiny, spherical particles used in the pharmaceutical and food industries. Microcrystalline cellulose is a naturally occurring, tasteless, odourless powder. Spray-drying is a common method for creating MCC spheres. This method involves atomizing a solution of MCC in water or another solvent and then drying the droplets to create solid spheres.

The final product can be altered by adjusting the size, shape, and porosity of MCC spheres during the spray-drying procedure. MCC spheres are frequently used in tablet formulations to increase the mechanical strength and speed of tablet disintegration because of their high degree of compressibility.They can also be used as a flow agent in dry powder inhalers and as a filler in capsules.

MCC spheres are valued for their capacity to function in a variety of formulations as a binder, filler, disintegrant, or flow agent. They are simple to handle and process due to their smooth surface and excellent flow characteristics. MCC spheres are safe for use in food and pharmaceutical applications because they are also very pure and biocompatible.

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Benefits of Microcrystalline cellulose (MCC) sphere

  • Content uniformity
  • Chemically and biologically inert.
  • Ease of coating process and ideal for capsule.
  • Insoluble in water
  • Narrow particle size distribution with perfect spherical shape and structure.
  • MCC spheres are tasteless and odorless.
  • Low friability and high mechanical strength.
  • Wide range of particle size available.
  • Ideal for sensitive actives due to the inertness of Micro Crystalline Cellulose.

Reasons to use Microcrystalline cellulose (MCC) sphere.

  • Excellent drug content and size uniformity.
  • Customized Release Profile.
  • Higher drug stability.
  • Multiple-Active pharmaceutical ingredients's can be combined in one-unit dose.
  • Reduced risk of sudden dose dumping.
  • Perfect tool for combinatory and controlled release products.

Regulatory Information on Microcrystalline cellulose (MCC) Spheres

  • CAS- No. 9004-34-6
  • In compliance with EP, USP, IP.
  • Plant origin
  • BSE/TSE free
  • Allergen free, Gluten free, Sugar free
  • Residual Solvent free

Storage conditions for Microcrystalline cellulose (MCC):

  • Protect from excessive temperature
  • Protect from moisture
  • Protect from freezing
  • Re-evaluation 36 months from date of manufacturing

General properties related to Neutral Spheres


  • Improved capsule properties
  • Consistent flow properties
  • Controlled release
  • Biocompatible
  • Inertness
  • Versatility


  • Tablet manufacturing
  • Capsule manufacturing
  • Dry powder inhalers
  • Flavor encapsulation
  • Food coating
  • Personal care products

Formats Available

  • Coated MCC spheres
  • Flavored MCC spheres
  • Different-sizes MCC spheres
  • MCC beadlets
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